Enzymes called collagenases target the structural causes under the skin, where cellulite starts. It’s thought that QWO works by releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen. How QWO works in moderate to severe cellulite is not fully understood.

No. QWO is an injectable treatment option that is thought to target a primary structural cause of cellulite— the fibrous septae. The exact mechanism for the treatment of moderate to severe cellulite is unknown.

Your doctor will determine if you are an appropriate candidate for QWO.

QWO is only approved for treatment of moderate to severe cellulite in the buttocks of adult women. Endo Aesthetics is continuing to investigate additional areas of treatment.

Each treatment visit may include up to two treatment areas. QWO injections will be given three weeks apart for a total of three treatment visits.

There are risks associated with this product. QWO may cause serious side effects including: allergic (hypersensitivity) reactions, including anaphylaxis, and injection site bruising.1 These are not all the side effects of QWO.

QWO is now available throughout the United States at aesthetic healthcare practitioners’ offices.

Do not receive QWO if you: are allergic to collagenase or to any of the ingredients in QWO, or have an active infection at the treatment area.

QWO may cause serious side effects, including:

• Allergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have hives, trouble breathing, low blood pressure, swollen face, chest pain, dizziness or fainting after receiving QWO;
• Injection site bruising Before receiving QWO, tell your healthcare provider if you:
  • have a bleeding problem
  • are pregnant or may become pregnant, nursing or plan to nurse. You and your healthcare provider should decide if you will receive QWO or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant).

The most common side effects of QWO include: injection site bruising, pain, areas of hardness, itching, redness, discoloration, swelling and warmth in the treatment area.